Review The SDS Document
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Formula
C15H21N3O3S
MW
323.41
Purity
>97%
Solubility (DMSO Mg/MI)
60
Bio Chemical Notes
Gliclazide is used in treatment of non-insulin-dependent diabetes mellitus (NIDDM). It binds to the beta-cell sulfonyl urea receptor (SUR1) which subsequently blocks the ATP sensitive potassium channels. This leads to a resulting decrease in potassium efflux. Ref: Drugs.1993; 46 (1), 92-125.