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Formula
C8H11N3O3S
MW
229.25
Purity
>97%
Solubility (DMSO Mg/MI)
40
Bio Chemical Notes
Lamivudine is used in treatment of HIV infection and chronic hepatitis B (HBV). It is phosphorylated intracellularly to its active 5'-triphosphate metabolite, lamivudine triphosphate (L-TP). This is then incorporated into viral DNA by HIV reverse transcriptase. Ref: Clinical Pharmacokinetics. 1999; 36 (1), 41-66.