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Formula
C18H28ClN3O5S
MW
433.96
Purity
>97%
Solubility (DMSO Mg/MI)
INSOLUBLE
Bio Chemical Notes
A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites, likely binding and altering DNA. Also, beneficial effects in lupus erythematosus and chronic rheumatoid arthritis. Accumulates in white blood cells, stabilizing lysosomal membranes and inhibiting the activity of collagenase and the proteases that cause cartilage breakdown. Ref: Seminars in Arthritis and Rheumatism. 1993; 23 (2), Supplement 1, 82