Selected New Building Blocks

  • N-(3,4-dichlorophenyl)-1H-indazole-5-carboxamide (NTZ-1006)
  • N-(3-chloro-4-fluorophenyl)-1H-indazole-5-carboxamide (NTZ-1032)
  • N-(3,4-difluorophenyl)-1H-indazole-5-carboxamide (NTZ-1034)
  • N-(3-chloro-4-fluorophenyl)-1-methyl-1H-indazole-5-carboxamide (NTZ-1441)
  • N-(3-chloro-4-fluorophenyl)-2-methyl-2H-indazole-5-carboxamide (NTZ-1442)
  • N-(3,4-dichlorophenyl)-1-methyl-1H-indazole-5-carboxamide (NTZ-1091)
  • N-(3,4-dichlorophenyl)-2-methyl-2H-indazole-5-carboxamide (NTZ-1092)
  • N-(3,4-difluorophenyl)-1-methyl-1H-indazole-5-carboxamide (NTZ-1471)
  • N-(3,4-difluorophenyl)-2-methyl-2H-indazole-5-carboxamide (NTZ-1472)
  • (6-bromo-1-benzofuran-2-yl)methanol
  • benzyl N-[(2S,4S)-2-phenyl-1,2,3,4-tetrahydroquinolin-4-yl]carbamate
  • benzyl N-[(2S,4S)-2-(furan-2-yl)-1,2,3,4-tetrahydroquinolin-4-yl]carbamate
  • ethyl (2S,4S)-4-{[(benzyloxy)carbonyl]amino}-1,2,3,4-tetrahydroquinoline-2-carboxylate
  • ethyl (2S,4S)-4-amino-1,2,3,4-tetrahydroquinoline-2-carboxylate hydrochloride
  • benzyl N-[(2R,3R)-2-phenyloxetan-3-yl]carbamate
  • benzyl (3aS,4R,9bS)-4-phenyl-1H,2H,3H,3aH,4H,5H,9bH-pyrrolo[3,2-c]quinoline-1-carboxylate
  • ethyl (2S,4S)-4-formamido-1,2,3,4-tetrahydroquinoline-2-carboxylate
  • 1-[(2S,4S)-2-phenyl-1,2,3,4-tetrahydroquinolin-4-yl]pyrrolidin-2-one
Selected New Fragments & Screening

  • 2-acetyl-4-bromophenyl 4-methylbenzoate
  • rac-tert-butyl (R)-(1-methyl-1H-imidazol-2-yl)[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl carbonate
  • 4-bromo-2,6-bis(propan-2-yl)phenol
  • 5-amino-1-[(2-chlorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide
  • 2-acetyl-4-chlorophenyl 4-methylbenzoate
  • 6-chloro-2-(2-methylphenyl)-4H-chromen-4-one
  • rac-tert-butyl N-[(1R)-1-carbamoyl-2-phenylethyl]carbamate
  • 6-chloro-2-(3-methylphenyl)-4H-chromen-4-one
  • 2-acetyl-4-chlorophenyl 2-methylbenzoate
  • 2-acetyl-4-chlorophenyl benzoate
  • 6-chloro-2-(3-methoxyphenyl)-4H-chromen-4-one
  • rac-tert-butyl N-[(1R)-1-cyano-2-phenylethyl]carbamate
  • 1,1,3,3-tetraethoxy-2-methylpropane
  • 4-bromo-2-{[(tert-butoxy)carbonyl]amino}benzoic acid
  • N'-ethanimidoyl(tert-butoxy)carbohydrazide
  • spiro[indene-1,4'-piperidine]
  • 4-(methoxycarbonyl)-1-methylpyridin-1-ium iodide
  • rac-(3R)-thiolan-3-ol
AMT Compounds

  • Methyl Potassium Oxalate
  • Dimesna (Disodium 2,2'-dithiobisethane sulfonate)
  • (3S,4S,5S,7S)-6-methyl-2-oxa-6- azatricyclo[3.3.1.0^{3,7}]nonan-4-ol
  • 5-bromobenzo[c][1,2,5]thiadiazole
  • 6-chloropurine riboside
  • Benzo[c][1,2,5]oxadiazole-5-boronic acid pinacol ester
  • 2-(3,4-dihydro-2H-1-benzopyran-6-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • tert-Butyl 2-(2-methyl-1-nitropropan-2-yl)hydrazinecarboxylate
  • Detomidine Hydrochloride
  • Apricitabine
  • 2-ethoxy-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile
  • tert-butyl 4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-carboxylate
  • tert-butyl 4-[5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]piperazine-1-carboxylate
  • 2-methyl-1-nitroprop-1-ene
  • 4-(3-((2-Methoxyethoxy)carbonyl)ureido)phenylboronic acid pinacol ester
  • 6-(tetramethyl-1,3,2-dioxaborolan-2-yl)-2H-chromen-2-one
  • 1-[2-(2-aminoethoxy)ethoxy]-2-(2-azidoethoxy)ethane
  • N-[3-(pyrrolidin-1-yl)propyl]-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine
Interesting Chiral Amines

  • (S)-6-bromochroman-4-amine hydrochloride
  • (R)-2-(3,5-difluorophenyl)pyrrolidine hydrochloride
  • (R)-4-(1-aminoethyl)benzoic acid hydrochloride
  • (S)-methyl 2-amino-3-(5-methylpyridin-2-yl)propanoate dihydrochloride
  • (S)-methyl 4-(piperidin-2-yl)benzoate hydrochloride
  • (R)-1-(4-((trifluoromethyl)thio)phenyl)ethanamine hydrochloride
  • (5R)-5-amino-5-phenylpentanoic acid hydrochloride
  • (R)-1-(4-fluorophenyl)but-3-en-1-amine hydrochloride
  • (2S)-2-amino-3-[4-(trifluoromethoxy)phenyl]propanoic acid hydrochloride
  • methyl 3-((1R)-1-amino-2-hydroxyethyl)benzoate hydrochloride
  • (1S)-1-(furan-2-yl)ethan-1-amine hydrochloride
  • (R)-cyclopropyl(3-methoxyphenyl)methanamine hydrochloride
  • (1S)-1-(thiophen-2-yl)ethan-1-amine hydrochloride
  • (R)-6-(trifluoromethoxy)chroman-4-amine hydrochloride
  • 4-((2S)pyrrolidin-2-yl)-2,2-difluorobenzo[d]1,3-dioxolane hcl
  • (S)-3-amino-5-hydroxyindane hydrochloride
  • 3-((1S)-1-amino-2,2,2-trifluoroethyl)benzoic acid hcl
  • (R)-2,3-dihydrobenzofuran-3-amine hydrochloride

BIOCHEMICALS

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BUILDING BLOCKS

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FRAGMENTS & SCREENING

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from the blog
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