Review The SDS Document
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Formula
C6H14O6S2
MW
246.30
Purity
>97%
Solubility (DMSO Mg/MI)
40
Bio Chemical Notes
Busulfan has a selective immunosuppressive effect on bone marrow and has been used in the palliative treatment of chronic myeloid leukemia. Alkylating agent that forms carbonium ions that alkylate DNA, which results in the interference of DNA replication and RNA transcription (leading to cell apoptosis). Ref: Leukemia & Lymphoma. 2012; 53 (5) , 973-981.