Custom Enquiry
We aim to give you a response from a qualified scientist within a hour.
Product Details
Formula
C27H32F2N8
MW
506.61
Purity
>98%
Solubility (DMSO Mg/MI)
80
Storage (Powder)
3 Years -20°C
Storage (Solvent)
1 Year -80°C
Indication
Breast Cancer
Mode Of Action
inhibitor
Drug Status
Approved
Target Name
Cyclin-dependent kinase 4 (CDK4)/Cyclin-dependent kinase 6 (CDK6)
Research Area
CANCER
Research Area Sub Group
Anticancer
Pharmacology
ENZYMES
Pharmacology Area Sub Group
Kinase
Bio Chemical Notes
Abemaciclib is a cell cycle inhibitor selective for CDK4/6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively