Review The SDS Document
DOWNLOADProduct Details
Formula
C10H12N4O3
MW
236.23
Purity
>97%
Solubility (DMSO Mg/MI)
40
Bio Chemical Notes
Didanosine is used in combination with other antiretroviral agents, in the treatment of HIV-1 infection. It is metabolized intracellularly by cellular enzymes to dideoxyadenosine triphosphate (ddATP), which competitively inhibits the HIV reverse transcriptase enzyme and blocks natural dATP binding. Ref: Drugs. 1992; 44 (1), 94-116.