Equipment & Experience
Key Organics has modern facilities and is well equipped to manage most types of chemistry. We have a well equipped analytics laboratory and highly experienced staff from many of the UK’s leading universities.
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What We Have
Key Organics is committed to acquiring a wide range of the latest state-of-the-art equipment for its chemists to ensure the highest quality and service to its customers.
- 360m2 lab space, containing 38 Fume Hoods
- Up to 30 litre vessels with temperature range of -20°C to +150°C
- Dedicated 10lt vacuum jacketed vessel capable of -70°C via Huber 905 Unistat including precision and reproducible reaction dosing system.
- Biotage 150 and Flash 75 large scale flash chromatography units capable of handling up to kg quantities of materials. Access to a wide range of separation media resulting in very low impurity contamination
- Biotage Isolera One and Isolera LS automated flash systems
- Teledyne ISCO ACCQPrep® HP150
- Buchi 220 pro rotary evaporator with up to 20 litre capacity offering excellent and efficient solvent removal with minimal fugitive losses maximising environmental protection
- 2” wiped-film still specifically for the distillation of heat sensitive materials
- 500ml to 2lt vacuum jacketed vessels capable of full calorimetry and reaction profiling at -78°C to +150°C reaction temperatures.
- Hastelloy and stainless steel autoclaves up to 4 litres capable of undertaking high pressure (200 bar) and high temperature (+200°C) hydrogenation, ring reductions and carbonylations.
- Advion Interchim Scientific ASAP® MS with Plate Express
- Biotage microwave
- Anton Parr sealed tube reactor
- Six bespoke walk in Fume Hoods, fully flexible from benchtop to scale up chemistry
- Two bespoke walk in scrubbed and wash down Fume Hoods to enable chemistry that needs an extra level of safety and containment
- Two vented hoods fully accessible from all sides for general small-scale chemistry
- 100m2 lab space
- 40m2 office and storage space
- Designed to be fully flexible to allow our chemists to carry out chemistry from benchtop to 30 litre scale (in future, potential to house up to 100 litre vessels)
- Fully serviced high spec design
New Scale Up Lab Profile
Our analytical department is equipped with the following instrumentation
- NMR: Bruker 400MHz AVIII NMR equipped with a 1H/13C multinuclear probe capable of performing routine 1D experiments plus variable temperature experiments
- LC/LCMS: Agilent 1260 LC multiple wavelength UV/Vis detector, ELSD, 6130 Single Quadrupole MS, Agilent 1260 LC infinity II with IQ MS and Agilent 1100 HPLC
- Gas Chromatography: Agilent 7890 GC, with flame ionisation detector
- DSC 25: TA Instruments
- KF: Mettler-Toledo C30s
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