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Mode Of Action
Oxo-5-alpha-steroid 4-dehydrogenase (SRD5A)
Research Area Sub Group
Pharmacology Area Sub Group
Bio Chemical Notes
In aerobic bacteria it reversibly inhibits oxidoreductive enzymes including tyrosinase, mitochondrial enzymes, thioredoxin reductase, 5-alpha-reductase, and DNA polymerases. In anaerobic bacteria, azelaic acid impedes glycolysis. Ref: Drugs. 1991, 41 (5), 780-798.