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Formula
C8H5F3N2OS
MW
234.20
Purity
>97%
Solubility (DMSO Mg/MI)
40
Bio Chemical Notes
Used for the treatment of amyotrophic lateral sclerosis (motor neuron disease or Lou Gehrig's disease). Riluzole acts as a voltage-dependent sodium channel blocker on glutamatergic nerve terminals, resulting in inhibition of glutamic acid release and subsequent blockade of glutamatergic neurotransmission in the CNS. Ref: Neurology 1996; 47 (6) Suppl 4; 233S-241S.