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Formula
C15H9FN2O3
MW
284.25
Purity
>95%
Solubility (DMSO Mg/MI)
50
Bio Chemical Notes
PTC124 (Ataluren) selectively induces ribosomal read-through of premature but not normal termination codons, with EC50 of 0.1 μM, may provide treatment for genetic disorders caused by nonsense mutations (e.g. CF caused by CFTR nonsense mutation). Phase 3.