Review The SDS Document
DOWNLOADProduct Details
Formula
C19H14Cl2N2O3S
MW
421.29
Purity
>98%
Solubility (DMSO Mg/MI)
80
Storage (Powder)
3 Years -20°C
Storage (Solvent)
1 Year -80°C
Indication
Carcinoma
Mode Of Action
inhibitor
Drug Status
Approved
Target Name
Smoothened homolog (SMO)
Research Area
CANCER
Research Area Sub Group
Anticancer
Pharmacology
GPCRs/7-TM RECEPTORS
Pharmacology Area Sub Group
Smoothened Receptors
Bio Chemical Notes
Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM.