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Product Details
Formula
C13H16N4O
MW
244.3
Purity
>98%
Solubility (DMSO Mg/MI)
15
Storage (Powder)
3 Years -20°C
Storage (Solvent)
1 Year -80°C
Indication
Lung Cancer
Mode Of Action
inhibitor
Drug Status
Investigational
Target Name
Poly [ADP-ribose] polymerase (PARP)
Research Area
CANCER
Research Area Sub Group
Anticancer
Pharmacology
ENZYMES
Pharmacology Area Sub Group
Polymerase
Bio Chemical Notes
Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It is inactive to SIRT2.