Review The SDS Document
DOWNLOADProduct Details
Formula
C21H23NO6
MW
385.42
Purity
>95%
Solubility (DMSO Mg/MI)
5
Storage (Powder)
3 Years -20°C
Storage (Solvent)
1 Year -80°C
Indication
N/A
Mode Of Action
inhibitor
Drug Status
Approved
Target Name
Tubulin (TUB)
Research Area
OTHER
Research Area Sub Group
Antiarthritic
Pharmacology
STRUCTURAL
Pharmacology Area Sub Group
Cytoskeleton & Motor Proteins
Bio Chemical Notes
Colchiceine is a metabolite of Colchicine which is used in the relief of pain in attacks of acute gouty arthritis. It decreases leukocyte chemotaxis and phagocytosis and inhibits the formation and release of a chemotactic glycoprotein. Currently under investigation as anticancer agent through its inhibition of microtubule polymerisation. Ref: Current Med Chem.2013; 20 (7), 892