Review The SDS Document
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Formula
C9H11FN2O5
MW
246.20
Purity
>97%
Solubility (DMSO Mg/MI)
40
Bio Chemical Notes
Doxifluridine is a prodrug of the active metabolite 5-fluorouracil which is used for the treatment of multiple actinic or solar keratoses. It inhibits the incorporation of purine or pyrimidine into DNA during the S phase. The main mechanism is assumed to be the binding of the deoxyribonucleotide (FdUMP) and the folate cofactor (N5