Review The SDS Document
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Formula
C12H17N5O4
MW
295.30
Purity
>97%
Solubility (DMSO Mg/MI)
40
Bio Chemical Notes
An antiviral used in the treatment of hepatitis B. Competes with the natural substrate deoxyguanosine triphosphate, and so inhibits activity of HBV polymerase (reverse transcriptase) including base priming, reverse transcription of the negative strand from the pregenomic messenger RNA, and synthesis of the positive strand of HBV DNA. Ref: J. Virol. 2007; 81 (8), 3992-4001.