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Formula
C14H19N5O4
MW
321.34
Purity
>97%
Solubility (DMSO Mg/MI)
64
Storage (Powder)
3 Years -20°C
Storage (Solvent)
1 Year -80°C
Indication
N/A
Mode Of Action
inhibitor
Drug Status
Approved
Target Name
Herpes simplex virus DNA polymerase UL30 (HSV UL30)
Research Area
INFECTION
Pharmacology
ENZYMES
Pharmacology Area Sub Group
Polymerase
Bio Chemical Notes
Famciclovir is used for the treatment of acute herpes zoster (shingles), and is the oral form of Penciclovir (KS-5016). Kinases within the herpes virus phosphorylate the penciclovir molecule, which is then able to inhibit DNA polymerase. Ref: Antimicrob Agents Chem 1992; 36 (12); 2747-2757.