Review The SDS Document
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Formula
C21H27N5O4S
MW
445.54
Purity
>97%
Solubility (DMSO Mg/MI)
80
Bio Chemical Notes
Glipizide is used in control of hyperglycemia and its associated symptomatology in patients with non-insulin-dependent diabetes mellitus (NIDDM; type II). It binds to ATP-sensitive potassium-channel receptors on the pancreatic cell surface causing depolarization and so stimulates calcium ion influx through voltage-sensitive calcium channels. Ref: European Journal of Pharmacology. 2000; 388 (2), 147