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Mode Of Action
Angiotensin-converting enzyme (ACE)
Research Area Sub Group
Pharmacology Area Sub Group
Bio Chemical Notes
Lisinopril is used in treatment of hypertension and symptomatic congestive heart failure. A competitive inhibitor of angiotensin-converting enzyme (ACE), thereby effecting the conversion of angiotensin I (ATI) to angiotensin II (ATII). Ref: Drugs. 1988; 35 (6), 646-669.