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Formula
C23H34O5
MW
390.52
Purity
>97%
Solubility (DMSO Mg/MI)
20
Bio Chemical Notes
Mevastatin is a cholesterol-lowering agent. It is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase and has a binding affinity 10,000 times more than the HMG-CoA substrate. It has also been shown to inhibit cdk2 activating phosphorylation. Ref: The Journal of Biological Chemistry. 2003; 278, 4840-4846.