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Formula
C13H8Cl2N2O4
MW
327.13
Purity
>97%
Solubility (DMSO Mg/MI)
5
Bio Chemical Notes
Niclosamide is used in the treatment of tapeworm and intestinal fluke infections. The exact mechanism of action is unknown, but it appears that Niclosamide uncouples oxidative phosphorylation in the scolex and proximal segments of the adult tapeworm and stimulates adenosine triphosphatase activity of mitochondria, resulting in death. Ref: Annals of Internal Medicine 1985; 102 (4); 550-551.