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Formula
C28H25ClF3N7O2
MW
584.01
Purity
>97%
Solubility (DMSO Mg/MI)
33
Bio Chemical Notes
Nilotinib inhibits the tyrosine kinase activity of the BCR-ABL protein, the cause of chronic myelogenous leukaemia. This is done by fitting into the ATP-binding site of BCR-ABL . Ref: British Journal of Cancer. 2006; 94, 1765