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Formula
C24H23FN4O3
MW
434.47
Purity
>97%
Solubility (DMSO Mg/MI)
34
Bio Chemical Notes
Oloparib is an inhibitor of PARP1 (IC50 = 5nM) and PARP2 (IC50 = 1nM), and is being investigated as a possilbe treatment for cancer patients with BRCA1 or 2 mutations. Ref: Cancer Research 2012; 72; 5588.