Review The SDS Document
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Formula
C14H17ClN2O
MW
264.76
Purity
>97%
Solubility (DMSO Mg/MI)
61
Bio Chemical Notes
PNU 282987 is a highly selective alpha7 nAChR agonist (Ki = 26 nM). Derivatives may be used in treatment of schizophrenia, although PNU-282987 is not suitable for use in humans because of excessive inhibition of the hERG antitarget. Ref: Journal of Pharmacology. 2005; 312 (3), 1213-1222.