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Formula
C28H30ClN5O4S
MW
568.09
Purity
>97%
Solubility (DMSO Mg/MI)
90
Bio Chemical Notes
A selective inhibitor of MET tyrosine kinase (IC50 = 0.01 microM). Induces cell cycle arrest and apoptosis. Abrogates cell motility and migration as well as tumor angiogenesis. Ref: Cancer Res. 2005; 65,1479