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Formula
C26H37NO7
MW
475.58
Purity
>97%
Solubility (DMSO Mg/MI)
90
Bio Chemical Notes
Tolterodine inhibits carbachol-induced contractions of isolated strips of urinary bladder in a concentration-dependent competitive manner. It is a muscarinic M1-5 receptor antagonist, and has been found to bind preferentially to the muscarinic receptors in the bladder (Ki=2.7 nM), heart (Ki=1.6 nM), and cerebral cortex (Ki=0.75 nM) from guinea pig. Ref: European Journal of Pharmacology 1997; 327 (2-3); 195-207.