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Formula
C14H23ClN6O5
MW
390.83
Purity
>97%
Solubility (DMSO Mg/MI)
70
Bio Chemical Notes
Valganciclovir is a prodrug of ganciclovir, esterases form the active drug and it is then phosphorylated to the monophosphate by viral protein kinase (cytomegalovirus), followed by further phosphorylation by cellular kinases. This inhibits viral DNA polymerase. Ref: Drugs. 1990; 39 (4), 597-638.