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Formula
C21H22Cl2N4OS
MW
449.4
Purity
>97%
Solubility (DMSO Mg/MI)
10
Storage (Powder)
3 Years -20°C
Storage (Solvent)
1 Year -80°C
Indication
N/A
Mode Of Action
antagonist
Drug Status
Approved
Target Name
Dopamine D2 receptor (D2R)
Research Area
NEUROLOGY
Research Area Sub Group
Antipsychotic
Pharmacology
GPCRs/7-TM RECEPTORS
Pharmacology Area Sub Group
Dopamine Receptors
Bio Chemical Notes
A 5-HT2A and dopamine D2 antagonist. It also shows potent interaction with 5-HT1A where it acts as an agonist, and 5-HT2C and 5-HT1D receptors. Ziprasidone has moderate affinity for serotonin and norepinephrine reuptake inhibition. Ref: J Clin Psychiatry 2003; 64 (suppl 19); 6-12.